Guiding the GMS Program is the GMS Strategic Framework 2012–2022 and the GMS Regional Investment Framework 2013–2017, the latter which consists of a $50 billion pipeline of potential investments.
The GMS Program has nine priority sectors represented by working groups and forums for agriculture, energy, environment, human resource development, investment, telecommunications, tourism, transport infrastructure, and transport and trade facilitation.
The GMS Working Group on Environment (WGE) oversees the GMS Core Environment Program, the flagship environmental cooperation initiative under the GMS Program. With support from the Environment Operations Center, the WGE aims to facilitate cross-sector environmental collaboration under the GMS Program with key sectors being agriculture, energy, tourism, and transport.